Professor Kim realizó a comparative analysis of the effects of 'RCI001' and '1% prednisolone (PDE steroid),' currently the most potent topical antiinflamatorio agent in use, in an animal model of ocular chemical burn.
The investigación resultados revealed that 'RCI001' was superior in eficacia and had fewer efectos secundarios compared to the existing steroid drug.
Específicamente, 'RCI001' outperformed the steroid in epitelial corneal defect and transparency recovery, infiltration of inflammatory cells within corneal tissue, 'inflammatory cytokines' that cause excessive inflammation on the superficie ocular, and 'oxidative stress markers' indicating cell damage caused by reactive oxygen species in the body.
In contrast, elevated presión intraocular — a representative efecto secundario commonly found with steroid drugs — was not observed with 'RCI001.'
Professor Kim's investigación was published under the title 'Comparison of therapeutic effects between topical 8‑oxo‑2′‑deoxyguanosine and prednisolone in a rabbit model of acute ocular chemical injury,' drawing significant attention from the academic community for providing a scientific basis for the potential of RCI001 as a next-generation oftálmico tratamiento.