Publications

Patents & Papers

Our patent portfolio and key academic publications protecting and advancing RudaCure's core technology and research achievements.

10

Patent Families

35

Total Filings

5

Granted

11

Countries

7

Total Papers

Patent Portfolio

Securing global intellectual property rights for core ion channel drug discovery technologies.

RCI001
2 families

Pharmaceutical Composition Containing 8-oxo-2'-deoxyguanosine for Treating Corneal Disease

Inventors: 정명희, 김동현

Korea|10-1816277|Granted
PCT|KR2017/011068
USA|US10675294|Granted

Eye Drop Formulations in Aqueous Solution Comprising 8-oxo-2'-deoxyguanosine

Inventors: 김동현, 박설규, 이동진, 김선경

Korea|10-2023-0121513
PCT|PCT/KR2023/018842
USA|18/813,805
Europe|EP24197366.8
China|202380069678.2
Japan|JP7886490|Granted|PDF
Australia|2023465099
New Zealand|829708
Canada|3302629
Brazil|11-2026-002888-2
Mexico|26/02889
Thailand|2601001700
RCI001U
1 family

2'-Deoxyguanosine Derivatives or Salts Thereof and Pharmaceutical Compositions

Inventors: 김용호, 김승훈, 구영아, 김완훈

Korea|10-2023-0167240
PCT|PCT/KR2024/018577
RCI002
3 families

Pharmaceutical Composition for Treating TRPV1-Mediated Diseases (GDF11 Active Ingredient)

Inventors: 김용호, 김승훈, 전하원, 하유승

Korea|10-2339414|Granted
PCT|PCT/KR2020/018895
USA|17/137392
Europe|20914763.6
China|2020800866718
Japan|JP 7663882|Granted

A Novel Peptide and the Use Thereof

Inventors: 김용호, 김승훈, 전하원, 장예원

Korea|10-2023-0026404
PCT|PCT/KR2023/016946
USA|18/686,660
Europe|23855750.8
Japan|2024-513214
China|202380094047.6

Composition for Pain Treatment

Inventors: 김승훈, 김윤연, 김재승, 최승혁

Korea|10-2025-0122722
PCT|PCT/KR2025/013324
RCI003
1 family

8-oxo-2'-Deoxyguanosine Derivatives

Inventors: 김용호, 김승훈, 강혜린, 조하늘, 용혜임, 김완훈

Korea|10-2023-0195845
RCI009
2 families

Pharmaceutical Composition for Prevention or Treatment of Pruritus Comprising TRPV1 Antagonist

Inventors: 김승훈, 신지윤, 김윤연, 용혜임, 구연수

Korea|10-2026-0043871

Pharmaceutical Composition for Prevention or Treatment of Dry Eye Disease Comprising TRPV1 Antagonist

Inventors: 김승훈, 신지윤, 김윤연, 구영아, 최가은

Korea|10-2026-0043872
기타
1 family

Hypothalamus-Pituitary Biochip and Manufacturing Method Thereof

Inventors: -

Korea|10-2902348
Trademarks
RUDACURE42류
40-1790156Granted
MEDDIXON05류
40-1790164Granted
RuCIA42류
40-2025-0146222

Key Research Papers

RudaCure's key research achievements published in domestic and international SCI-indexed journals.

2025
Original Article

Efficacy of RCI001 as a Therapeutic Candidate in a Primary Sjögren Syndrome Mouse Model

Hyereen Kang, Young-ho Jung, Jayoon Moon, Jin Suk Ryu, Chang Ho Yoon, Yong Ho Kim, Mee Kum Kim, Dong Hyun Kim

Cornea·10.1097/ICO.0000000000003696
2023
Original Article

Comparison of Corneal Epithelial Wound Healing between Topical RCI001, Solcoseryl, and Polydeoxyribonucleotide in the Murine Ocular Alkali Burn Model

Myung-Sun Song, Young Ah Ku, Seunghoon Kim, Myung Hee Chung, Yong Ho Kim, Dong Hyun Kim

Korean Journal of Ophthalmology·10.3341/kjo.2023.0019
2022
Original Article

Investigating the Anti-Inflammatory Effects of RCI001 for Treating Ocular Surface Diseases: Insight Into the Mechanism of Action

Seunghoon Kim, Ye Won Jang, Young-ah Ku, Yungyeong Shin, Md Mahbubur Rahman, Myung-Hee Chung, Yong Ho Kim, Dong Hyun Kim

Frontiers in Immunology·10.3389/fimmu.2022.850287
Original Article

Comparison of Therapeutic Effects between Topical 8-oxo-2'-deoxyguanosine and Corticosteroid in Ocular Alkali Burn Model

Dong Hyun Kim, Sang-Taek Im, Jin Young Yoon, Seunghoon Kim, Mee Kum Kim, Myung-Hee Chung, Chul-Kyu Park

Scientific Reports·10.1038/s41598-021-86440-7
Original Article

Ocular Distribution and Pharmacokinetics of 8-Oxo-2'-Deoxyguanosine: A Novel Therapeutic Candidate of Ocular Surface Diseases

Hyewon Chung, Yuseung Ha, Yong Ho Kim, Dong Hyun Kim, Dongseong Shin

Journal of Ocular Pharmacology and Therapeutics·10.1089/jop.2022.0054
Original Article

Short-Term Therapeutic Effects of Topical Corticosteroids on Refractory Dry Eye Disease: Clinical Usefulness of Matrix Metalloproteinase 9 Testing as a Response Prediction Marker

Kyung Jae Ryu, Seunghoon Kim, Mee Kum Kim, Hae Jung Paik, Dong Hyun Kim

Clinical Ophthalmology·10.2147/OPTH.S300047
Original Article

Improved Accuracy of Intraocular Lens Power Calculation by Preoperative Management of Dry Eye Disease

Jinsoo Kim, Mee Kum Kim, Yuseung Ha, Hae Jung Paik, Dong Hyun Kim

BMC Ophthalmology·10.1186/s12886-021-02129-5